Product Name :
Src Recombinant Rabbit Monoclonal Antibody [JF0947]

Predicted band size :
60 kDa

Observed band size :
60 kDa

Synonyms:
ASV antibody Avian sarcoma virus antibody c SRC antibody CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody cSrc antibody EC 2.7.10.2 antibody Neuronal CSRC tyrosine specific protein kinase antibody Neuronal SRC antibody Oncogene SRC antibody OTTHUMP00000174476 antibody 展开

Function :
The major translational products of the Src gene family are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences. By virtue of their common structural motifs, the Src family is composed of nine members in vertebrates, including c-Src, c-Yes, Fgr, Yrk, Fyn, Lyn, Hck, Lck and Blk. Src family kinases, which contain an amino-terminal cell membrane anchor followed by SH3 and SH2 domains, transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src family members are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular locations of Src family kinases may be important for the regulation of specific cellular processes, such as mitogenesis, cytoskeletal organization and membrane trafficking. c-Src (also designated pp60Src, Src p60 and proto-oncogene tyrosine protein kinase Src) is expressed in a broad range of tissue and cell types, although the highest levels of c-Src are detected in neuronal tissues and platelets. c-Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.

Antibody Type:
Recombinant Rabbit monoclonal Antibody

Immunogen :
Synthetic peptide within human Src aa 20-60.5-Chloroquinolin-8-amine site

Species reactivity:
Human, Mouse, Rat

Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC

Coupling :
unconjugated

Clone number:
JF0947

RRID:
AB_3070268

Form :
Liquid

Concentration :
1ug/ul

Storage instructions:
Store at +4℃ after thawing.1260381-44-9 Chemscene Aliquot store at -20℃ or -80℃.PMID:33382524 Avoid repeated freeze / thaw cycles.

Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Subtype:
IgG

Purification method :
Protein A affinity purified.

ELTSA :

Molecular weight :
Predicted band size: 60 kDa

Positive control :
HUVEC cell lysate, A549 cell lysate, PC-3M cell lysate, SH-SY5Y cell lysate, Wild-type HCT116 whole cell lysates, SK-OV-3, Hela, MCF-7, A431, human tonsil tissue, human breast carcinoma tissue, human kidney tissue, rat brain tissue, mouse kidney tissue, NIH/3T3, NIH/3T3 cell lysate.