Product Name :
2-Methyl-4-isothiazolin-3-one (CAS 2682-20-4)

Synonym :
N-Methyl-3-oxodihydro isothiazole; 2-Methyl-3(2H)-isothiazolone

Application :
2-Methyl-4-isothiazolin-3-one is a potent biocide useful for controlling microbial growth

CAS:
2682-20-4

Purity:
≥98.0%

Molecular Weight:
115.15

Formula :
C4H5NOS

Physical state:
Liquid

solubility :

Shipping Condition :
Store at room temperature

Melting point:

SMILES:
CN1C(=O)C=CS1

References:
:Contact sensitization to 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one in children. | Tosti, A., et al. 2003. Contact Dermatitis. 49: 215-6. PMID: 14996074Antifungal activities of bronopol and 2-methyl-4-isothiazolin-3-one (MT) against saprolegnia. | Oono, H. and Hatai, K. 2007. Biocontrol Sci. 12: 145-8. PMID: 18198720Three-phase hollow-fiber liquid-phase microextraction combined with HPLC-UV for the determination of isothiazolinone biocides in adhesives used for food packaging materials. | Rosero-Moreano, M., et al. 2014. J Sep Sci. 37: 272-80. PMID: 24302646Analysis of isothiazolinone preservatives in polyvinyl alcohol cooling towels used in Japan. | Kawakami, T., et al. 2014. J Environ Sci Health A Tox Hazard Subst Environ Eng. 49: 1209-17. PMID: 24967553In vitro activity of seven hospital biocides against Mycobacterium abscessus: Implications for patients with cystic fibrosis. | Caskey, S., et al. 2018. Int J Mycobacteriol. 7: 45-47. PMID: 29516885Development of a highly efficient electrochemical flow-through anode based on inner in-site enhanced TiO2-nanotubes array. | Chen, M., et al. 2020. Environ Int. 140: 105813. PMID: 32480113Degradation of a non-oxidizing biocide in circulating cooling water using UV/persulfate: Kinetics, pathways, and cytotoxicity. | Cui, J., et al. 2022. Chemosphere. 289: 133064. PMID: 34838601Functional and dynamic mitochondrial damage by chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) mixture in brain endothelial cell lines and rat cerebrovascular endothelium.1166831-45-3 Price | Kim, D.Price of 2223047-95-6 , et al.PMID:33645490 2022. Toxicol Lett. 366: 45-57. PMID: 35803525Analysis and control of fungal deterioration on the surface of pottery figurines unearthed from the tombs of the Western Han Dynasty. | Wang, Y., et al. 2022. Front Microbiol. 13: 956774. PMID: 36046016Contact allergy to a contaminant in Kathon CG in the guinea pig. | Bruze, M., et al. 1987. Derm Beruf Umwelt. 35: 165-8. PMID: 3691315Absorption and disposition of 14C-labelled Kathon biocide, a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, following intravenous or dermal administration to male Sprague-Dawley rats. | deBethizy, JD., et al. 1986. Food Chem Toxicol. 24: 43-9. PMID: 3949268The genetic toxicology of Kathon biocide, a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one. | Scribner, HE., et al. 1983. Mutat Res. 118: 129-52. PMID: 6410231Occupational dermatitis from isothiazolinones in the nylon production. | Valsecchi, R., et al. 1993. Dermatology. 187: 109-11. PMID: 8358097