Product Name :
Rae1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
dJ481F12.3 antibody dJ800J21.1 antibody FLJ30608 antibody Homolog of yeast Rae1 (Bharathi) mRNA associated protein of 41 kDa (Kraemer) antibody Homolog of yeast Rae1 mRNA associated protein of 41 kDa antibody MGC117333 antibody MGC126076 antibody MGC126077 antibody MIG 14 antibody MIG14 antibody 展开
Function :
Mrnp41 (mRNA-binding protein, 41-KD), also known as Rae1 protein homolog and mRNA export factor, is a 368 amino acid protein that binds mRNA and is involved in nucleocytoplasmic transport. Though characterized in both the nucleus and cytoplasm, mrnp41 is primarily localized to the nuclear pore complex in the nuclear envelope. Mutations in mrnp41 may result in the accumulation of poly(A)-containing mRNA in the nucleus, further supporting the role of mrnp41 as a primary nuclear exporter of mRNA. Along with Nup98, mrnp41 has been shown to regulate E-cadherin, an activating subunit of the anaphase-promoting complex complex, which results in the prevention of securin degradation, therefore suggesting that mrnp41 may play a potential role in maintaining euploidy.6-(tert-Butoxy)-6-oxohexanoic acid site Also, during mitosis, both mrnp41 and NuMA have been shown to be required for bipolar spindle formation.(-)-Fucose Price
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within Human Rae1 aa 319-368 / 368.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069160
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33604792 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 41 kDa
Positive control :
PC-3, mouse testis tissue, rat testis tissue, LOVO, MCF-7, PC-3M.